abstract：BACKGROUND:Appendectomy for acute appendicitis is an effective, universally accepted procedure performed more than 300,000 times annually in the United States. It is generally believed that appendicitis progresses invariably from early inflammation to later gangrene and perforation, and that appendectomy is required fo...

journal_title：Surgical infections

authors： Mason RJ

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Mycobacterium avium-intracellulare (MAI) is a well-described pathogen in patients with acquired immune deficiency syndrome (AIDS). However, peritonitis and severe sepsis as a complication of disseminated MAI is rare. We report a case that represents the first successful use of recombinant human activated pro...

journal_title：Surgical infections

authors： Ullery B,Pieracci FM,Hydo LJ,Eachempati SR,Barie PS

更新日期：2008-06-01 00:00:00

abstract：PURPOSE:To discover the incidence of postoperative surgical site infections in non-immunocompromised pediatric patients with an absolute neutrophil count (ANC) < or = 1,000 preoperatively. METHODS:Office and hospital charts of consecutive patients with preoperative ANC < or = 1,000 undergoing elective surgery over a t...

journal_title：Surgical infections

authors： Taylor GS,Cartwright PC,Snow BW

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:To determine the effects of hypertonic saline (HS) as fluid resuscitation during or after major spinal surgery. We hypothesized that the administration of HS perioperatively would decrease morbidity and mortality rates. METHODS:A two-year retrospective, pair-matched, case-control study of adult patients (57...

journal_title：Surgical infections

authors： Charalambous MP,Swoboda SM,Lipsett PA

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Accurate diagnosis and initial management of skin and soft tissue infections (SSTIs) are essential to providing adequate care to patients. Methicillin-resistant Staphylococcus aureus (MRSA) is one of the leading causes of SSTIs, and surgeons and other healthcare providers should assess these infections caref...

journal_title：Surgical infections

authors： Sawyer RG

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Bacterial infections are a well-known complication of traumatic amputations. In cases involving contact with soil or water contaminated with manure, one also must be aware of infections with fungi, particularly Scedosporium spp. We report on an immunocompetent trauma patient with an infection caused by a rec...

journal_title：Surgical infections

authors： Kooijman CM,Kampinga GA,de Hoog GS,Goudswaard WB,Reijnen MM

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:There is a paucity of data regarding whether sterile handling of endotracheal tubes (ETTs) impacts the incidence and prevalence of pneumonia in the emergency, urgent, or elective clinical scenarios. Intensive care units employ infection control and reduction schemes to reduce pneumonia rates. METHODS:A MEDL...

journal_title：Surgical infections

authors： Cheung N,Betro G,Luckianow G,Napolitano L,Kaplan LJ

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Multi-drug resistant (MDR) organisms in intensive care units (ICUs) are a growing concern. The emergence of several infections with MDR Acinetobacter baumannii prompted a review of cases and evaluation of the efficacy of intervention. OBJECTIVE:To determine the rate of clinical cure, the incidence of drug r...

journal_title：Surgical infections

authors： Trottier V,Namias N,Pust DG,Nuwayhid Z,Manning R,Marttos AC Jr,Dunham MB,Schulman CI,McKenney MG

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Previously, we developed an infection model by intraperitoneal (IP) injection of Klebsiella pneumoniae. The high early mortality rate prompted a study of the effect of gentamicin on the disease course. METHODS:Infection was induced in Balb/c mice by IP inoculation of 10(3) colony-forming units (cfu) of K. p...

journal_title：Surgical infections

authors： Woods DR,Peyton JC,Franklin GA,Turina M,Cheadle WG

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Ventilator-associated pneumonia (VAP) is a frequent complication during recovery of severely traumatized patients. The primary objective of this study was to determine if prophylactic administration of aerosolized ceftazidime reduced the incidence of VAP in high-risk injured patients without altering the inc...

journal_title：Surgical infections

authors： Claridge JA,Edwards NM,Swanson J,Fabian TC,Weinberg JA,Wood C,Croce MA

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Infection is the most common postoperative complication within the surgical wound and during severe trauma. In spite of the use of modern sterile techniques and prophylaxis, infection continues to be a leading cause of death in these patients. Therefore, it has become crucial to develop new alternatives to p...

journal_title：Surgical infections

authors： Aviles H,O'Donnell P,Sun B,Sonnenfeld G

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Low plasma concentrations and genetic polymorphisms of mannan-binding lectin (MBL) have been associated with infectious disease complications during various conditions. The present study examined the nature and expression of MBL deficiency during a surgery-induced acute-phase response. METHODS:Blood was sam...

journal_title：Surgical infections

authors： Van Till JW,Boermeester MA,Modderman PW,Van Sandick JW,Hart MH,Gisbertz SS,Van Lanschot JJ,Aarden LA

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The exact mechanism of fever and urosepsis after percutaneous procedures has not been established. This research studied the frequency of fever after percutaneous nephrolithotomy (PCNL) and the contributing factors. METHODS:In a cross-sectional study, from September 2003 to March 2004, all 217 p...

journal_title：Surgical infections

authors： Sharifi Aghdas F,Akhavizadegan H,Aryanpoor A,Inanloo H,Karbakhsh M

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:By definition, the term "surgical infection" implies that surgery plays the major role in therapy, whereas antimicrobial chemotherapy is only supplementary. Despite this view, the efficacy of such drugs is relevant, and for this reason, drug activity surveillance is necessary, especially for opportunistic an...

journal_title：Surgical infections

authors： Rodriguez CN,Rodriguez-Morales AJ,Garcia A,Pastran B,Meijomil P

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:A substantial proportion of operative procedures are complicated by infections, either remote from or related to the surgical site. These infections account for substantive morbidity and health care costs. With limited research funds available to study interventions designed to either prevent or reduce the m...

journal_title：Surgical infections

authors： Nathens AB,Cook CH,Machiedo G,Moore EE,Namias N,Nwariaku F

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:One of the main benefits of minimally invasive surgery compared with open surgery is the significant reduction in the incidence of postoperative infections. Possible explanations include the smaller incision, minimal use of central venous catheters for parenteral nutrition, faster mobilization, r...

journal_title：Surgical infections

authors： Boni L,Benevento A,Rovera F,Dionigi G,Di Giuseppe M,Bertoglio C,Dionigi R

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Surgical infections, and sepsis in particular, are characterized by extensive release of mediators. Our laboratories have been interested in understanding how these substances contribute to morbidity and mortality during various stages of surgical infections in order to develop new and more effective therape...

journal_title：Surgical infections

authors： Aasen AO,Wang JE

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Central venous catheters (CVCs) are used to deliver a variety of therapies, as well as for measurement of hemodynamic parameters. The major associated complication is catheter-related blood stream infection (CRBSI). METHOD:Review of the pertinent English-language literature. RESULTS:The incidence of CRBSI ...

journal_title：Surgical infections

authors： Bacuzzi A,Cecchin A,Del Bosco A,Cantone G,Cuffari S

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The approach to perioperative antibiotic prophylaxis, bowel preparation, and postoperative routines in elective colorectal resections has changed over the last two decades. The aim of this national survey was to document the current methods of perioperative management of those patients scheduled for elective...

journal_title：Surgical infections

authors： Shpitz B,Reissman P,Rabau M,Ziv Y

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Conceptually, appropriateness of antibiotic therapy includes choice of agent relative to susceptibility of pathogens as well as dosing, timing of onset, and duration of therapy, but is most commonly considered in terms of choice of antibiotic. It has been suggested that inappropriate antibiotic selection can...

journal_title：Surgical infections

authors： Barie PS,Hydo LJ,Shou J,Larone DH,Eachempati SR

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Surgical site infections are the third most common healthcare-associated infection, often leading to prolonged hospital stay and excessive expenditures. Management of these infections has become more challenging due to rising rates of multi-drug-resistant organisms and few new antibiotic options. METHODS:Th...

journal_title：Surgical infections

authors： Weber DJ,Rutala WA

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Hyperglycemia is a common occurrence in critically ill patients. Recent evidence has demonstrated improved survival in patients in surgical intensive care units (SICUs) receiving "tight glycemic control." The mechanisms of this survival advantage are not well understood. METHODS:A review of the English lang...

journal_title：Surgical infections

authors： Taylor JH,Beilman GJ

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Over the last half-decade, substantial breakthroughs have taken place in terms of routine therapy of critically ill patients. The combination of these strategies has the potential to result in improvement in the overall outcomes for patients in intensive care units. METHODS:A focused review was undertaken o...

journal_title：Surgical infections

authors： Beilman GJ

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:An untreated hand infection can lead rapidly to tissue destruction and permanent disability. METHODS:Review of the pertinent English literature. RESULTS:Early diagnosis and timely, effective intervention is crucial to treatment. Anatomically, the hand consists of multiple potential spaces and tissue planes...

journal_title：Surgical infections

authors： Spann M,Talmor M,Nolan WB

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Patients with serious intraabdominal infections (IAI) who subsequently acquire nosocomial infections (NI) have been shown to have adverse outcomes. We evaluated factors that put patients at risk for developing NI and examined the effect of the NI on outcomes. METHODS:This study was a retrospective review of...

journal_title：Surgical infections

authors： Merlino JI,Yowler CJ,Malangoni MA

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Severe trauma leads to hematopoietic failure and bone marrow (BM) dysfunction that manifests clinically as a persistent anemia and leukopenia. The impact of severe trauma and its associated hyperadrenergic state on erythropoiesis has not been described. The aim of this study was to demonstrate the effects of...

journal_title：Surgical infections

authors： Fonseca RB,Mohr AM,Wang L,Clinton E,Sifri ZC,Rameshwar P,Livingston DH

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The emergence of multi-drug resistant microorganisms presents a critical problem for patients undergoing surgery. Acidic pH, which is produced by oxidized regenerated cellulose (ORC), is a broad-spectrum physiological detriment to survival of microorganisms known to cause surgical infections. The purpose of ...

journal_title：Surgical infections

authors： Spangler D,Rothenburger S,Nguyen K,Jampani H,Weiss S,Bhende S

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Fungal sinusitis has been reported increasingly in immunocompetent patients. However, the most effective, appropriate mode of therapy has not been determined. MATERIALS AND METHODS:In this retrospective study, we examined the records of 110 immunocompetent patients with chronic sinusitis who had undergone s...

journal_title：Surgical infections

authors： Hadi U,Bitar M,Hachem R,Saade R,Husni R,Raad I

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Controversy continues to exist regarding the immunomodulatory effects of cellular blood transfusions in the fields of oncology, transplantation, and infectious diseases. Numerous studies have correlated transfusion with hospital-acquired infection, but the impact of transfusion on infection-related mortality...

journal_title：Surgical infections

authors： Hughes MG,Evans HL,Lightfoot L,Chong TW,Smith RL,Raymond DP,Pelletier SJ,Claridge JA,Pruett TL,Sawyer RG

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Antimicrobial resistance is a growing problem in the intensive care setting. This study was designed to evaluate the trends in bacterial prevalence and changes in antibiotic resistance at a large university hospital over the past decade. Antimicrobial resistance data were compared among the surgical intensiv...

journal_title：Surgical infections

authors： Franklin GA,Moore KB,Snyder JW,Polk HC Jr,Cheadle WG

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:This report is a review of the published literature for studies of triclosan that address mechanism of action, efficacy on skin and in the oral cavity, and the potential for development of resistance. METHODS:Triclosan citations from the past three decades were searched using Medline and other search engine...

journal_title：Surgical infections

authors： Gilbert P,McBain AJ

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:The pathogenicity of Enterococcus in polymicrobial surgical infections is controversial. The objective of this analysis was two-fold. The impact of Enterococcus on clinical outcome was assessed in adults with complicated intra-abdominal (IAI), complicated skin and skin structure (CSSSI), or acute pelvic (PI)...

journal_title：Surgical infections

authors： Teppler H,McCarroll K,Gesser RM,Woods GL

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Computed tomography (CT) is used increasingly to evaluate suspected cases of acute appendicitis (AA) in the emergency department (ED). This prospective study was performed to test the hypothesis that the evaluation of AA by CT in the ED remains suboptimal and that erroneous interpretation diminishes its util...

journal_title：Surgical infections

authors： Maluccio MA,Covey AM,Weyant MJ,Eachempati SR,Hydo LJ,Barie PS

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:The pathogenic organisms responsible for the manifestations of secondary peritonitis have been well characterized through almost 30 years of experimental and clinical studies. Enteric gram-negative organisms and anaerobes predominate, with Escherichia coli and Bacteroides fragilis, respectively, being the mo...

journal_title：Surgical infections

authors： Nathens AB

更新日期：2001-07-01 00:00:00

abstract：:Antibiotics are important in the prophylaxis and treatment of surgical infections as well as in the management of nosocomial infections acquired postoperatively in surgical patients. Surgeons encounter a range of infectious conditions, including established single-pathogen infections of soft tissues, polymicrobial int...

journal_title：Surgical infections

authors： Fry DE

更新日期：2001-01-01 00:00:00

abstract：:Multiple organ dysfunction syndrome (MODS) is caused by an overwhelming, uncontrolled systemic inflammatory response that is activated by a number of hostile stimuli including sepsis, hypovolemic shock, and severe trauma resulting in massive tissue injury. The indiscriminate activation of the inflammatory response due...

journal_title：Surgical infections

authors： Maier RV

更新日期：2000-10-01 00:00:00

abstract：:Broad-spectrum beta-lactam antibiotics have several advantages in the treatment of intra-abdominal infections. These agents are effective against gram-negative rods and anaerobes, reach therapeutic levels rapidly after parenteral administration, and, in the absence of penicillin allergy, generally exhibit low toxicity...

journal_title：Surgical infections

authors： Powell LL,Wilson SE

更新日期：2000-01-01 00:00:00